CATH Domain 4lf3F00

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CATH Classification

Level	CATH Code	Description
	4	Few Secondary Structures
	4.10	Irregular
	4.10.1240	Hormone receptor fold
	4.10.1240.10	GPCR, family 2, extracellular hormone receptor domain

Domain Context

CATH Clusters

Superfamily	GPCR, family 2, extracellular hormone receptor domain
Functional Family	Glucagon receptor

Enzyme Information

UniProtKB Entries (1)

GLR_HUMAN

Homo sapiens

Glucagon receptor

PDB Structure

PDB	4LF3
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Inhibitory mechanism of an allosteric antibody targeting the glucagon receptor. Mukund, S., Shang, Y., Clarke, H.J., Madjidi, A., Corn, J.E., Kates, L., Kolumam, G., Chiang, V., Luis, E., Murray, J., Zhang, Y., Hotzel, I., Koth, C.M., Allan, B.B. J.Biol.Chem.