CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphoribosylformylglycinamidine synthase, linker domain
Functional Family Phosphoribosylformylglycinamidine synthase

Enzyme Information

6.3.5.3
Phosphoribosylformylglycinamidine synthase.
based on mapping to UniProt P74881
ATP + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + H(2)O = ADP + phosphate + 2-(formamido)-N(1)-(5-phospho-D- ribosyl)acetamidine + L-glutamate.

UniProtKB Entries (1)

P74881
PUR4_SALTY
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Phosphoribosylformylglycinamidine synthase

PDB Structure

PDB 4L78
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Importance of hydrophobic cavities in allosteric regulation of formylglycinamide synthetase: insight from xenon trapping and statistical coupling analysis
Tanwar, A.S., Goyal, V.D., Choudhary, D., Panjikar, S., Anand, R.
Plos One