CATH Domain 4k8dA03

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.390	Enolase-like; domain 1
	3.30.390.30	FAD/NAD-linked reductase, C-terminal dimerisation domain

Domain Context

CATH Clusters

Superfamily	3.30.390.30
Functional Family	Dihydrolipoyl dehydrogenase

Enzyme Information

1.16.1.1

Mercury(II) reductase.

based on mapping to UniProt P00392

Hg + NADP(+) + H(+) = Hg(2+) + NADPH.

UniProtKB Entries (1)

MERA_PSEAI

Pseudomonas aeruginosa

Mercuric reductase

PDB Structure

PDB	4K8D
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structure of the C136(42)A/C141(47)A double mutant of Tn501 MerA in complex with NADPH and Hg2+ Dong, A., Falkowski, M., Malone, M., Miller, S.M., Pai, E.F. to be published