CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.420.40
Functional Family

Enzyme Information
Acetate kinase.
based on mapping to UniProt A0QLU8
ATP + acetate = ADP + acetyl phosphate.
-!- While purified enzyme from Escherichia coli is specific for acetate, others have found that the enzyme can also use propanoate as a substrate, but more slowly. -!- Acetate can be converted into the key metabolic intermediate acetyl- CoA by coupling acetate kinase with EC -!- Both this enzyme and EC play important roles in the production of propanoate.

UniProtKB Entries (1)

Mycobacterium avium 104
Acetate kinase

PDB Structure

External Links
Primary Citation
Increasing the structural coverage of tuberculosis drug targets.
Baugh, L., Phan, I., Begley, D.W., Clifton, M.C., Armour, B., Dranow, D.M., Taylor, B.M., Muruthi, M.M., Abendroth, J., Fairman, J.W., Fox, D., Dieterich, S.H., Staker, B.L., Gardberg, A.S., Choi, R., Hewitt, S.N., Napuli, A.J., Myers, J., Barrett, L.K., Zhang, Y., Ferrell, M., Mundt, E., Thompkins, K., Tran, N., Lyons-Abbott, S., Abramov, A., Sekar, A., Serbzhinskiy, D., Lorimer, D., Buchko, G.W., Stacy, R., Stewart, L.J., Edwards, T.E., Van Voorhis, W.C., Myler, P.J.
Tuberculosis (Edinb)