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CATH Domain 4is6B02

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.40 Immunoglobulin-like
Homologous Superfamily 2.60.40.10 Immunoglobulins

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family HLA class II histocompatibility antigen, DRB1-1 beta chain

Enzyme Information

UniProtKB Entries (1)

P40967
PMEL_HUMAN
Homo sapiens
Melanocyte protein PMEL

PDB Structure

PDB 4IS6
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure-Based Design of Altered MHC Class II-Restricted Peptide Ligands with Heterogeneous Immunogenicity.
Chen, S., Li, Y., Depontieu, F.R., McMiller, T.L., English, A.M., Shabanowitz, J., Kos, F., Sidney, J., Sette, A., Rosenberg, S.A., Hunt, D.F., Mariuzza, R.A., Topalian, S.L.
J.Immunol.
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