CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family GTP-binding nuclear protein Ran

Enzyme Information

UniProtKB Entries (2)

P62826
RAN_HUMAN
Homo sapiens
GTP-binding nuclear protein Ran
P30822
XPO1_YEAST
Saccharomyces cerevisiae S288C
Exportin-1

PDB Structure

PDB 4HAT
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1.
Sun, Q., Carrasco, Y.P., Hu, Y., Guo, X., Mirzaei, H., Macmillan, J., Chook, Y.M.
Proc.Natl.Acad.Sci.USA