CATH Domain 4h8eA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.1180	Undecaprenyl pyrophosphate synthetase
	3.40.1180.10	Decaprenyl diphosphate synthase-like

Domain Context

CATH Clusters

Superfamily	Decaprenyl diphosphate synthase-like
Functional Family	(2E,6E)-farnesyl-diphosphate-specific ditrans,polycis-undecaprenyl-diphosphate synthase

Enzyme Information

2.5.1.-

Transferring alkyl or aryl groups, other than methyl groups.

based on mapping to UniProt P60477

UniProtKB Entries (1)

ISPT_STAAN

Staphylococcus aureus subsp. aureus N315

Isoprenyl transferase

PDB Structure

PDB	4H8E
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Antibacterial drug leads targeting isoprenoid biosynthesis. Zhu, W., Zhang, Y., Sinko, W., Hensler, M.E., Olson, J., Molohon, K.J., Lindert, S., Cao, R., Li, K., Wang, K., Wang, Y., Liu, Y.L., Sankovsky, A., de Oliveira, C.A., Mitchell, D.A., Nizet, V., McCammon, J.A., Oldfield, E. Proc.Natl.Acad.Sci.USA