CATH Classification
Domain Context
CATH Clusters
| Superfamily | Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A |
| Functional Family | Meprin A subunit |
Enzyme Information
| 3.4.24.63 |
Meprin B.
based on mapping to UniProt Q16820
Hydrolysis of proteins, including azocasein, and peptides. Hydrolysis of 5-His-|-Leu-6, 6-Leu-|-Cys-7, 14-Ala-|-Leu-15 and 19-Cys-|-Gly-20 bonds in insulin B chain.
-!- Inhibited by EDTA and 1,10-phenanthroline, but not by phosphoramidon, captopril or thiorphan. -!- Belongs to peptidase family M12A.
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UniProtKB Entries (1)
| Q16820 |
MEP1B_HUMAN
Homo sapiens
Meprin A subunit beta
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PDB Structure
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| Organism | |
| Primary Citation |
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