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1 keywords

CATH Domain 4gahB00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.10 Roll
Topology 3.10.129 Thiol Ester Dehydrase; Chain A
Homologous Superfamily 3.10.129.10 Hotdog Thioesterase

Domain Context

CATH Clusters

Superfamily Hotdog Thioesterase
Functional Family Acyl-coenzyme A thioesterase THEM4

Enzyme Information

3.1.2.2
Palmitoyl-CoA hydrolase.
based on mapping to UniProt Q5T1C6
Palmitoyl-CoA + H(2)O = CoA + palmitate.
-!- Also hydrolyzes CoA thioesters of other long-chain fatty acids.

UniProtKB Entries (1)

Q5T1C6
THEM4_HUMAN
Homo sapiens
Acyl-coenzyme A thioesterase THEM4

PDB Structure

PDB 4GAH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Correlation of structure and function in the human hotdog-fold enzyme hTHEM4.
Zhao, H., Lim, K., Choudry, A., Latham, J.A., Pathak, M.C., Dominguez, D., Luo, L., Herzberg, O., Dunaway-Mariano, D.
Biochemistry
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