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1 keywords

CATH Domain 4flmB00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.1820 alpha/beta hydrolase

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family S-formylglutathione hydrolase

Enzyme Information

3.1.2.12
S-formylglutathione hydrolase.
based on mapping to UniProt P40363
S-formylglutathione + H(2)O = glutathione + formate.
-!- Also hydrolyzes S-acetylglutathione, more slowly.

UniProtKB Entries (1)

P40363
SFGH_YEAST
Saccharomyces cerevisiae S288C
S-formylglutathione hydrolase

PDB Structure

PDB 4FLM
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A role for His-160 in peroxide inhibition of S. cerevisiae S-formylglutathione hydrolase: Evidence for an oxidation sensitive motif.
Legler, P.M., Leary, D.H., Hervey, W.J., Millard, C.B.
Arch.Biochem.Biophys.
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