×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

1 keywords

CATH Domain 4f8eA02

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.2020  

Domain Context

CATH Clusters

Superfamily 3.40.50.2020
Functional Family Ribose-phosphate pyrophosphokinase 1

Enzyme Information

2.7.6.1
Ribose-phosphate diphosphokinase.
based on mapping to UniProt P60891
ATP + D-ribose 5-phosphate = AMP + 5-phospho-alpha-D-ribose 1-diphosphate.
-!- dATP can also act as donor.

UniProtKB Entries (1)

P60891
PRPS1_HUMAN
Homo sapiens
Ribose-phosphate pyrophosphokinase 1

PDB Structure

PDB 4F8E
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A small disturbance, but a serious disease: the possible mechanism of D52H-mutant of human PRS1 that causes gout
Chen, P., Li, J., Ma, J., Teng, M., Li, X.
Iubmb Life
CATH-Gene3D is a Global Biodata Core Resource Learn more...