CATH Domain 4e5eB00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.91	Restriction Endonuclease
	3.40.91.90	Influenza RNA-dependent RNA polymerase subunit PA, endonuclease domain

Domain Context

CATH Clusters

Superfamily	Influenza RNA-dependent RNA polymerase subunit PA, endonuclease domain
Functional Family

Enzyme Information

UniProtKB Entries (1)

Q5EP34_9INFA

Influenza A virus (A/Viet Nam/1203/2004(H5N1))

Polymerase acidic protein

PDB Structure

PDB	4E5E
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural and Biochemical Basis for Development of Influenza Virus Inhibitors Targeting the PA Endonuclease. Dubois, R.M., Slavish, P.J., Baughman, B.M., Yun, M.K., Bao, J., Webby, R.J., Webb, T.R., White, S.W. Plos Pathog.