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1 keywords

CATH Domain 4e36A04

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.25 Alpha Horseshoe
Topology 1.25.50 Zincin-like fold
Homologous Superfamily 1.25.50.20  

Domain Context

CATH Clusters

Superfamily 1.25.50.20
Functional Family Leucyl-cystinyl aminopeptidase

Enzyme Information

3.4.11.-
Aminopeptidases.
based on mapping to UniProt Q6P179

UniProtKB Entries (1)

Q6P179
ERAP2_HUMAN
Homo sapiens
Endoplasmic reticulum aminopeptidase 2

PDB Structure

PDB 4E36
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A common single nucleotide polymorphism in endoplasmic reticulum aminopeptidase 2 induces a specificity switch that leads to altered antigen processing.
Evnouchidou, I., Birtley, J., Seregin, S., Papakyriakou, A., Zervoudi, E., Samiotaki, M., Panayotou, G., Giastas, P., Petrakis, O., Georgiadis, D., Amalfitano, A., Saridakis, E., Mavridis, I.M., Stratikos, E.
J.Immunol.
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