1 keywords

CATH Domain 4druA01

CATH Classification

Domain Context

CATH Clusters

Superfamily
Functional Family -

PDB Structure

PDB 4DRU
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure-based macrocyclization yields hepatitis C virus NS5B inhibitors with improved binding affinities and pharmacokinetic properties.
Cummings, M.D., Lin, T.I., Hu, L., Tahri, A., McGowan, D., Amssoms, K., Last, S., Devogelaere, B., Rouan, M.C., Vijgen, L., Berke, J.M., Dehertogh, P., Fransen, E., Cleiren, E., van der Helm, L., Fanning, G., Van Emelen, K., Nyanguile, O., Simmen, K., Raboisson, P., Vendeville, S.
Angew.Chem.Int.Ed.Engl.