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1 keywords

CATH Domain 4dk8C00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.565 Retinoid X Receptor
Homologous Superfamily 1.10.565.10 Retinoid X Receptor

Domain Context

CATH Clusters

Superfamily Retinoid X Receptor
Functional Family Oxysterols receptor LXR-alpha isoform 1

Enzyme Information

UniProtKB Entries (1)

Q15788
NCOA1_HUMAN
Homo sapiens
Nuclear receptor coactivator 1

PDB Structure

PDB 4DK8
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Discovery of a new binding mode for a series of liver X receptor agonists.
Kopecky, D.J., Jiao, X.Y., Fisher, B., McKendry, S., Labelle, M., Piper, D.E., Coward, P., Shiau, A.K., Escaron, P., Danao, J., Chai, A., Jaen, J., Kayser, F.
Bioorg.Med.Chem.Lett.
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