CATH Classification

Domain Context

CATH Clusters

Superfamily DNA Methylase, subunit A, domain 2
Functional Family DNA (cytosine-5)-methyltransferase

Enzyme Information

2.1.1.37
DNA (cytosine-5-)-methyltransferase.
based on mapping to UniProt P13864
S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
-!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/ -!- Formerly EC 2.1.1.73.

UniProtKB Entries (1)

P13864
DNMT1_MOUSE
Mus musculus
DNA (cytosine-5)-methyltransferase 1

PDB Structure

PDB 4DA4
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure-Based Mechanistic Insights into DNMT1-Mediated Maintenance DNA Methylation.
Song, J., Teplova, M., Ishibe-Murakami, S., Patel, D.J.
Science