CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Ribosomal protein S6 kinase

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt P51812
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

P51812
KS6A3_HUMAN
Homo sapiens
Ribosomal protein S6 kinase alpha-3

PDB Structure

PDB 4D9U
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles.
Serafimova, I.M., Pufall, M.A., Krishnan, S., Duda, K., Cohen, M.S., Maglathlin, R.L., McFarland, J.M., Miller, R.M., Frodin, M., Taunton, J.
Nat.Chem.Biol.