CATH Domain 4ci2B01

Level	CATH Code	Description
	2	Mainly Beta
	2.170	Beta Complex
	2.170.150	Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A
	2.170.150.20	Peptide methionine sulfoxide reductase.

Superfamily	Peptide methionine sulfoxide reductase.
Functional Family	Cereblon, isoform CRA_c

Q16531	DDB1_HUMAN Homo sapiens DNA damage-binding protein 1
P0CF65	CRBN_CHICK Gallus gallus Protein cereblon

PDB	4CI2
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure of the Ddb1-Crbn E3 Ubiquitin Ligase in Complex with Thalidomide. Fischer, E.S., Bohm, K., Lydeard, J.R., Yang, H., Stadler, M.B., Cavadini, S., Nagel, J., Serluca, F., Acker, V., Lingaraju, G.M., Tichkule, R.B., Schebesta, M., Forrester, W.C., Schirle, M., Hassiepen, U., Ottl, J., Hild, M., Beckwith, R.E.J., Harper, J.W., Jenkins, J.L., Thoma, N.H. Nature