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1 keywords

CATH Domain 4cfoB02

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.530 Lysozyme
Homologous Superfamily 1.10.530.10  

Domain Context

CATH Clusters

Superfamily 1.10.530.10
Functional Family Membrane-bound lytic murein transglycosylase C

Enzyme Information

4.2.2.n1
Peptidoglycan lytic exotransglycosylase.
based on mapping to UniProt P0C066
Exolytic cleavage of the (1->4)-beta-glycosidic linkage between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc) residues in peptidoglycan, from either the reducing or the non-reducing ends of the peptidoglycan chains, with concomitant formation of a 1,6-anhydrobond in the MurNAc residue.

UniProtKB Entries (1)

P0C066
MLTC_ECOLI
Escherichia coli K-12
Membrane-bound lytic murein transglycosylase C

PDB Structure

PDB 4CFO
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure and Cell Wall Cleavage by Modular Lytic Transglycosylase Mltc of Escherichia Coli.
Artola-Recolons, C., Lee, M., Bernardo-Garcia, N., Blazquez, B., Hesek, D., Bartual, S.G., Mahasenan, K.V., Lastochkin, E., Pi, H., Boggess, B., Meindl, K., Uson, I., Fisher, J.F., Mobashery, S., Hermoso, J.A.
Acs Chem.Biol.
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