CATH Classification

Domain Context

CATH Clusters

Superfamily 6.10.140.1030
Functional Family

Enzyme Information

3.1.-.-
Acting on ester bonds.
based on mapping to UniProt P23477
3.6.4.12
DNA helicase.
based on mapping to UniProt P23477
ATP + H(2)O = ADP + phosphate.
-!- DNA helicases utilize the energy from ATP hydrolysis to unwind double-stranded DNA. -!- Some of them unwind duplex DNA with a 3' to 5' polarity (1,3,5,8), other show 5' to 3' polarity (10,11,12,13) or unwind DNA in both directions (14,15). -!- Some helicases unwind DNA as well as RNA (4,9). -!- May be identical with EC 3.6.4.13 (RNA helicase).

UniProtKB Entries (1)

P23478
ADDA_BACSU
Bacillus subtilis subsp. subtilis str. 168
ATP-dependent helicase/nuclease subunit A

PDB Structure

PDB 4CEH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Basis for Translocation by Addab Helicase-Nuclease and its Arrest at Chi Sites.
Krajewski, W.W., Fu, X., Wilkinson, M., Cronin, N.B., Dillingham, M.S., Wigley, D.B.
Nature