CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
Superfamily | P-loop containing nucleotide triphosphate hydrolases |
Functional Family |
Enzyme Information
3.1.-.- |
Acting on ester bonds.
based on mapping to UniProt P23477
|
3.6.4.12 |
DNA helicase.
based on mapping to UniProt P23477
ATP + H(2)O = ADP + phosphate.
-!- DNA helicases utilize the energy from ATP hydrolysis to unwind double-stranded DNA. -!- Some of them unwind duplex DNA with a 3' to 5' polarity (1,3,5,8), other show 5' to 3' polarity (10,11,12,13) or unwind DNA in both directions (14,15). -!- Some helicases unwind DNA as well as RNA (4,9). -!- May be identical with EC 3.6.4.13 (RNA helicase).
|
UniProtKB Entries (1)
P23478 |
ADDA_BACSU
Bacillus subtilis subsp. subtilis str. 168
ATP-dependent helicase/nuclease subunit A
|
PDB Structure
PDB | 4CEH |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structural Basis for Translocation by Addab Helicase-Nuclease and its Arrest at Chi Sites.
Nature
|