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1 keywords

CATH Domain 4cdkE00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.10 Ribbon
Topology 2.10.220 Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A domain 2
Homologous Superfamily 2.10.220.10 Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A, domain 2

Domain Context

CATH Clusters

Superfamily Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A, domain 2
Functional Family R-spondin 3

Enzyme Information

UniProtKB Entries (2)

Q5SSZ7
ZNRF3_MOUSE
Mus musculus
E3 ubiquitin-protein ligase ZNRF3
Q2MKA7
RSPO1_HUMAN
Homo sapiens
R-spondin-1

PDB Structure

PDB 4CDK
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structures of Wnt-Antagonist Znrf3 and its Complex with R-Spondin 1 and Implications for Signaling.
Peng, W.C., De Lau, W., Madoori, P.K., Forneris, F., Granneman, J.C.M., Clevers, H., Gros, P.
Plos One
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