CATH Domain 4ca4A00

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.1090	Fimbrial-type adhesion domain

Domain Context

CATH Clusters

Superfamily	Fimbrial-type adhesion domain
Functional Family	Type 1 fimbrin D-mannose specific adhesin

Enzyme Information

UniProtKB Entries (1)

A2IC68_ECOLX

Escherichia coli

FimH

PDB Structure

PDB	4CA4
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Mutation of Tyr137 of the universal Escherichia coli fimbrial adhesin FimH relaxes the tyrosine gate prior to mannose binding. Rabbani, S., Krammer, E.M., Roos, G., Zalewski, A., Preston, R., Eid, S., Zihlmann, P., Prevost, M., Lensink, M.F., Thompson, A., Ernst, B., Bouckaert, J. IUCrJ