CATH Classification

Domain Context

CATH Clusters

Superfamily Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A, domain 2
Functional Family R-spondin 4

Enzyme Information

UniProtKB Entries (2)

Q5SSZ7
ZNRF3_MOUSE
Mus musculus
E3 ubiquitin-protein ligase ZNRF3
Q5M7L6
RSPO2_XENTR
Xenopus tropicalis
R-spondin-2

PDB Structure

PDB 4C9A
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural and Molecular Basis of Znrf3/Rnf43 Transmembrane Ubiquitin Ligase Inhibition by the Wnt Agonist R-Spondin.
Zebisch, M., Xu, Y., Krastev, C., Macdonald, B.T., Chen, M., Gilbert, R.J.C., He, X., Jones, E.Y.
Nat.Commun.