CATH Classification

Domain Context

CATH Clusters

Superfamily Vaccinia Virus protein VP39
Functional Family Protein arginine N-methyltransferase 7

Enzyme Information

2.1.1.321
Type III protein arginine methyltransferase.
based on mapping to UniProt Q922X9
S-adenosyl-L-methionine + [protein]-L-arginine = S-adenosyl-L- homocysteine + [protein]-N(omega)-methyl-L-arginine.
-!- Type III protein arginine methyltransferases catalyze the single methylation of one of the terminal nitrogen atoms of the guanidino group in an L-arginine residue within a protein. -!- Unlike type I and type II protein arginine methyltransferases, which also catalyze this reaction, type III enzymes do not methylate the substrate any further. -!- Cf. EC 2.1.1.319, EC 2.1.1.320 and EC 2.1.1.322. -!- Formerly EC 2.1.1.23, EC 2.1.1.124, EC 2.1.1.125 and EC 2.1.1.126.

UniProtKB Entries (1)

Q922X9
ANM7_MOUSE
Mus musculus
Protein arginine N-methyltransferase 7

PDB Structure

PDB
External Links
Method
Organism
Primary Citation
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