CATH Domain 4bxfB02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.10	Arc Repressor Mutant, subunit A
	1.10.10.1500	JmjC domain-containing ribosomal oxygenase (ROX), dimer domain

Domain Context

CATH Clusters

Superfamily	JmjC domain-containing ribosomal oxygenase (ROX), dimer domain
Functional Family	ribosomal oxygenase 2 isoform X1

Enzyme Information

1.14.11.-

With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors.

based on mapping to UniProt Q8IUF8

UniProtKB Entries (1)

RIOX2_HUMAN

Homo sapiens

Ribosomal oxygenase 2

PDB Structure

PDB	4BXF
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Ribosomal oxygenases are structurally conserved from prokaryotes to humans. Chowdhury, R., Sekirnik, R., Brissett, N.C., Krojer, T., Ho, C.H., Ng, S.S., Clifton, I.J., Ge, W., Kershaw, N.J., Fox, G.C., Muniz, J.R.C., Vollmar, M., Phillips, C., Pilka, E.S., Kavanagh, K.L., von Delft, F., Oppermann, U., McDonough, M.A., Doherty, A.J., Schofield, C.J. Nature