CATH Domain 4aouA00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.718	Isopropylmalate Dehydrogenase
	3.40.718.10	Isopropylmalate Dehydrogenase

Domain Context

CATH Clusters

Superfamily	Isopropylmalate Dehydrogenase
Functional Family

Enzyme Information

UniProtKB Entries (1)

A3DC45_CLOTH

Hungateiclostridium thermocellum ATCC 27405

Isocitrate dehydrogenase [NADP]

PDB Structure

PDB	4AOU
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The complex structures of isocitrate dehydrogenase from Clostridium thermocellum and Desulfotalea psychrophila suggest a new active site locking mechanism. Leiros, H.K., Fedoy, A.E., Leiros, I., Steen, I.H. Febs Open Bio