CATH Classification

Domain Context

CATH Clusters

Superfamily Bromodomain-like
Functional Family Bromodomain-containing protein 4

Enzyme Information

UniProtKB Entries (1)

O60885
BRD4_HUMAN
Homo sapiens
Bromodomain-containing protein 4

PDB Structure

PDB 3ZYU
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Inhibition of Bet Recruitment to Chromatin as an Effective Treatment for Mll-Fusion Leukaemia.
Dawson, M.A., Prinjha, R.K., Dittman, A., Giotopoulos, G., Bantscheff, M., Chan, W.I., Robson, S.C., Chung, C.W., Hopf, C., Savitski, M.M., Huthmacher, C., Gudgin, E., Lugo, D., Beinke, S., Chapman, T.D., Roberts, E.J., Soden, P.E., Auger, K.R., Mirguet, O., Doehner, K., Delwel, R., Burnett, A.K., Jeffrey, P., Drewes, G., Lee, K., Huntly, B.J., Kouzarides, T.
Nature