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1 keywords

CATH Domain 3ze5A00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.287 Helix Hairpins
Homologous Superfamily 1.10.287.3610  

Domain Context

CATH Clusters

Superfamily 1.10.287.3610
Functional Family Diacylglycerol kinase

Enzyme Information

2.7.1.107
Diacylglycerol kinase (ATP).
based on mapping to UniProt P0ABN1
ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate.
-!- Involved in synthesis of membrane phospholipids and the neutral lipid triacylglycerol. -!- Activity is stimulated by certain phospholipids. -!- In plants and animals the product 1,2-diacyl-sn-glycerol 3-phosphate is an important second messenger. -!- cf. EC 2.7.1.174.

UniProtKB Entries (1)

P0ABN1
KDGL_ECOLI
Escherichia coli K-12
Diacylglycerol kinase

PDB Structure

PDB 3ZE5
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of the Integral Membrane Diacylglycerol Kinase.
Li, D., Lyons, J.A., Pye, V.E., Vogeley, L., Aragao, D., Kenyon, C.P., Shah, S.T.A., Doherty, C., Aherne, M., Caffrey, M.
Nature
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