CATH Domain 3x0bA02

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.810	Phosphatidylinositol Phosphate Kinase Iibeta; Chain: A, domain 2
	3.30.810.10	2-Layer Sandwich

Superfamily	2-Layer Sandwich
Functional Family	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta

2.7.1.149

1-phosphatidylinositol-5-phosphate 4-kinase.

based on mapping to UniProt P78356

ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate = ADP + 1-phosphatidyl- 1D-myo-inositol 4,5-bisphosphate.

PI42B_HUMAN

Homo sapiens

Phosphatidylinositol 5-phosphate 4-kinase type-2 beta

PDB	3X0B
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The Lipid Kinase PI5P4K beta Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis Sumita, K., Lo, Y.H., Takeuchi, K., Senda, M., Kofuji, S., Ikeda, Y., Terakawa, J., Sasaki, M., Yoshino, H., Majd, N., Zheng, Y., Kahoud, E.R., Yokota, T., Emerling, B.M., Asara, J.M., Ishida, T., Locasale, J.W., Daikoku, T., Anastasiou, D., Senda, T., Sasaki, A.T. Mol.Cell