CATH Domain 3vamB02

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.70	Alpha-Beta Plaits
	3.30.70.330	RRM (RNA recognition motif) domain

Domain Context

CATH Clusters

Superfamily	3.30.70.330
Functional Family	U2 snRNP auxiliary factor large subunit

Enzyme Information

UniProtKB Entries (1)

U2AF2_HUMAN

Homo sapiens

Splicing factor U2AF 65 kDa subunit

PDB Structure

PDB	3VAM
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs. Jenkins, J.L., Agrawal, A.A., Gupta, A., Green, M.R., Kielkopf, C.L. Nucleic Acids Res.