CATH Domain 3uzcA00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.1070	Rhopdopsin 7-helix transmembrane proteins
	1.20.1070.10	Rhodopsin 7-helix transmembrane proteins

Domain Context

CATH Clusters

Superfamily	Rhodopsin 7-helix transmembrane proteins
Functional Family	Adenosine receptor A2

Enzyme Information

UniProtKB Entries (1)

AA2AR_HUMAN

Homo sapiens

Adenosine receptor A2a

PDB Structure

PDB	3UZC
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Discovery of 1,2,4-Triazine Derivatives as Adenosine A(2A) Antagonists using Structure Based Drug Design Congreve, M., Andrews, S.P., Dore, A.S., Hollenstein, K., Hurrell, E., Langmead, C.J., Mason, J.S., Ng, I.W., Tehan, B., Zhukov, A., Weir, M., Marshall, F.H. J.Med.Chem.