CATH Domain 3tw8D00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.300	P-loop containing nucleotide triphosphate hydrolases

Domain Context

CATH Clusters

Superfamily	P-loop containing nucleotide triphosphate hydrolases
Functional Family	Putative ras-related protein Rab-35

Enzyme Information

UniProtKB Entries (1)

DEN1B_HUMAN

Homo sapiens

DENN domain-containing protein 1B

PDB Structure

PDB	3TW8
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Insights regarding guanine nucleotide exchange from the structure of a DENN-domain protein complexed with its Rab GTPase substrate. Wu, X., Bradley, M.J., Cai, Y., Kummel, D., De La Cruz, E.M., Barr, F.A., Reinisch, K.M. Proc.Natl.Acad.Sci.USA