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CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.2130.30
Functional Family

Enzyme Information

2.1.1.256
tRNA (guanine(6)-N(2))-methyltransferase.
based on mapping to UniProt Q8U248
S-adenosyl-L-methionine + guanine(6) in tRNA = S-adenosyl-L-homocysteine + N(2)-methylguanine(6) in tRNA.
-!- The enzyme specifically methylates guanine(6) at N(2) in tRNA.

UniProtKB Entries (1)

Q8U248
TRM14_PYRFU
Pyrococcus furiosus DSM 3638
TRNA (guanine(6)-N2)-methyltransferase

PDB Structure

PDB 3TM4
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structures of the tRNA:m2G6 methyltransferase Trm14/TrmN from two domains of life.
Fislage, M., Roovers, M., Tuszynska, I., Bujnicki, J.M., Droogmans, L., Versees, W.
Nucleic Acids Res.
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