CATH Classification

Domain Context

CATH Clusters

Superfamily 2.70.40.10
Functional Family dUTP pyrophosphatase

Enzyme Information

UniProtKB Entries (1)

Q8II92
Q8II92_PLAF7
Plasmodium falciparum 3D7
Deoxyuridine 5'-triphosphate nucleotidohydrolase

PDB Structure

PDB 3T64
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Design, synthesis, and evaluation of 5'-diphenyl nucleoside analogues as inhibitors of the Plasmodium falciparum dUTPase.
Hampton, S.E., Baragana, B., Schipani, A., Bosch-Navarrete, C., Musso-Buendia, J.A., Recio, E., Kaiser, M., Whittingham, J.L., Roberts, S.M., Shevtsov, M., Brannigan, J.A., Kahnberg, P., Brun, R., Wilson, K.S., Gonzalez-Pacanowska, D., Johansson, N.G., Gilbert, I.H.
Chemmedchem