CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.10860 | Leucine Dehydrogenase, chain A, domain 1 |
Domain Context
CATH Clusters
| Superfamily | Leucine Dehydrogenase, chain A, domain 1 |
| Functional Family | Quinate/shikimate dehydrogenase |
Enzyme Information
| 1.1.1.282 |
Quinate/shikimate dehydrogenase.
based on mapping to UniProt Q8ZPR4
(1) L-quinate + NAD(P)(+) = 3-dehydroquinate + NAD(P)H. (2) Shikimate + NAD(P)(+) = 3-dehydroshikimate + NAD(P)H.
-!- The enzyme is found in bacteria (mostly, but not exclusively, Gram- positive bacteria), fungi, and plants. -!- It participates in the degradation of quinate and shikimate with a strong preference for NAD+ as a cofactor. -!- While the enzyme can act on both quinate and shikimate, activity is higher with the former.
|
UniProtKB Entries (1)
| Q8ZPR4 |
YDIB_SALTY
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Quinate/shikimate dehydrogenase
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PDB Structure
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| Primary Citation |
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