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1 keywords

CATH Domain 3sw9A00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.170 Beta Complex
Topology 2.170.270 Beta-clip-like
Homologous Superfamily 2.170.270.10 SET domain

Domain Context

CATH Clusters

Superfamily SET domain
Functional Family Euchromatic histone-lysine N-methyltransferase 2

Enzyme Information

2.1.1.-
Methyltransferases.
based on mapping to UniProt Q9H9B1
2.1.1.43
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q9H9B1
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

UniProtKB Entries (2)

O88508
DNM3A_MOUSE
Mus musculus
DNA (cytosine-5)-methyltransferase 3A
Q9H9B1
EHMT1_HUMAN
Homo sapiens
Histone-lysine N-methyltransferase EHMT1

PDB Structure

PDB 3SW9
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a.
Chang, Y., Sun, L., Kokura, K., Horton, J.R., Fukuda, M., Espejo, A., Izumi, V., Koomen, J.M., Bedford, M.T., Zhang, X., Shinkai, Y., Fang, J., Cheng, X.
Nat Commun
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