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1 keywords

CATH Domain 3slaA00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.25 Alpha Horseshoe
Topology 1.25.10 Leucine-rich Repeat Variant
Homologous Superfamily 1.25.10.10 Leucine-rich Repeat Variant

Domain Context

CATH Clusters

Superfamily Leucine-rich Repeat Variant
Functional Family

Enzyme Information

UniProtKB Entries (1)

P35222
CTNB1_HUMAN
Homo sapiens
Catenin beta-1

PDB Structure

PDB 3SLA
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
An intrinsically labile alpha-helix abutting the BCL9-binding site of beta-catenin is required for its inhibition by carnosic acid.
de la Roche, M., Rutherford, T.J., Gupta, D., Veprintsev, D.B., Saxty, B., Freund, S.M., Bienz, M.
Nat Commun
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