CATH Domain 3sa2A00

×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.430	Dihydrofolate Reductase, subunit A
	3.40.430.10	Dihydrofolate Reductase, subunit A

Domain Context

CATH Clusters

Superfamily	Dihydrofolate Reductase, subunit A
Functional Family	Dihydrofolate reductase

Enzyme Information

UniProtKB Entries (1)

Q81R22_BACAN

Bacillus anthracis

Dihydrofolate reductase

PDB Structure

PDB	3SA2
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	SAR studies of heterocyclic propargyl-linked TMP analogs to Bacillus dihydrofolate reductase Anderson, A.C., Beierlein, J.M., Viswanathan, K., Wright, D.L. to be published