CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
6 | Special |
|
6.10 | Helix non-globular |
|
6.10.140 | Helix Hairpins |
|
6.10.140.970 |
Domain Context
CATH Clusters
| Superfamily | 6.10.140.970 |
| Functional Family |
Enzyme Information
| 5.2.1.8 |
Peptidylprolyl isomerase.
based on mapping to UniProt Q0PAS1
Peptidylproline (omega=180) = peptidylproline (omega=0).
-!- The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A. -!- Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli. -!- The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively.
|
UniProtKB Entries (1)
| Q0PAS1 |
CBF2_CAMJE
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Putative peptidyl-prolyl cis-trans isomerase Cbf2
|
PDB Structure
| PDB | |
| External Links | |
| Method | |
| Organism | |
| Primary Citation |
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