1 keywords

CATH Domain 3r1gL01

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.40 Immunoglobulin-like
Homologous Superfamily 2.60.40.10 Immunoglobulins

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Immunoglobulin kappa chain variable 12-38

Enzyme Information

UniProtKB Entries (1)

P56817
BACE1_HUMAN
Homo sapiens
Beta-secretase 1

PDB Structure

PDB 3R1G
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A Therapeutic Antibody Targeting BACE1 Inhibits Amyloid-{beta} Production in Vivo.
Atwal, J.K., Chen, Y., Chiu, C., Mortensen, D.L., Meilandt, W.J., Liu, Y., Heise, C.E., Hoyte, K., Luk, W., Lu, Y., Peng, K., Wu, P., Rouge, L., Zhang, Y., Lazarus, R.A., Scearce-Levie, K., Wang, W., Wu, Y., Tessier-Lavigne, M., Watts, R.J.
Sci Transl Med