CATH Domain 3r1fA00

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.260	434 Repressor (Amino-terminal Domain)
	1.10.260.40	lambda repressor-like DNA-binding domains

Domain Context

CATH Clusters

Superfamily	lambda repressor-like DNA-binding domains
Functional Family

Enzyme Information

UniProtKB Entries (1)

ESPR_MYCTU

Mycobacterium tuberculosis H37Rv

Nucleoid-associated protein EspR

PDB Structure

PDB	3R1F
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	EspR, a key regulator of Mycobacterium tuberculosis virulence, adopts a unique dimeric structure among helix-turn-helix proteins. Rosenberg, O.S., Dovey, C., Tempesta, M., Robbins, R.A., Finer-Moore, J.S., Stroud, R.M., Cox, J.S. Proc.Natl.Acad.Sci.USA