CATH Domain 3qv9B02

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.20	Alpha-Beta Barrel
	3.20.20	TIM Barrel
	3.20.20.60	Phosphoenolpyruvate-binding domains

Domain Context

CATH Clusters

Superfamily	Phosphoenolpyruvate-binding domains
Functional Family	Pyruvate kinase

Enzyme Information

UniProtKB Entries (1)

Q4D9Z4_TRYCC

Trypanosoma cruzi strain CL Brener

Pyruvate kinase

PDB Structure

PDB	3QV9
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The trypanocidal drug suramin and other trypan blue mimetics are inhibitors of pyruvate kinases and bind to the adenosine site. Morgan, H.P., McNae, I.W., Nowicki, M.W., Zhong, W., Michels, P.A., Auld, D.S., Fothergill-Gilmore, L.A., Walkinshaw, M.D. J.Biol.Chem.