CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.70 | Cathepsin D, subunit A; domain 1 |
|
2.40.70.10 | Acid Proteases |
Domain Context
CATH Clusters
| Superfamily | Acid Proteases |
| Functional Family | Plasmepsin-2 |
Enzyme Information
| 3.4.23.38 |
Plasmepsin I.
based on mapping to UniProt P39898
Hydrolysis of the 33-Phe-|-Leu-34 bond in the alpha-chain of hemoglobin, leading to denaturation of molecule.
-!- Inhibited by pepstatin. -!- Belongs to peptidase family A1.
|
UniProtKB Entries (1)
| P39898 |
PLM1_PLAFA
Plasmodium falciparum
Plasmepsin-1
|
PDB Structure
| PDB | 3QS1 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structures of the free and inhibited forms of plasmepsin I (PMI) from Plasmodium falciparum.
J.Struct.Biol.
|
