CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.10 | Roll |
|
3.10.300 | 3-methyladenine DNA Glycosylase; Chain A |
|
3.10.300.10 | Methylpurine-DNA glycosylase (MPG) |
Domain Context
CATH Clusters
| Superfamily | Methylpurine-DNA glycosylase (MPG) |
| Functional Family | Putative 3-methyladenine DNA glycosylase |
Enzyme Information
| 3.2.2.21 |
DNA-3-methyladenine glycosylase II.
based on mapping to UniProt P29372
Hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine.
|
UniProtKB Entries (1)
| P29372 |
3MG_HUMAN
Homo sapiens
DNA-3-methyladenine glycosylase
|
PDB Structure
| PDB | 3QI5 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural Basis for the Inhibition of Human Alkyladenine DNA Glycosylase (AAG) by 3,N4-Ethenocytosine-containing DNA.
J.Biol.Chem.
|