CATH Domain 3qebZ02

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.150	DNA polymerase; domain 1
	1.10.150.20	5' to 3' exonuclease, C-terminal subdomain

Domain Context

CATH Clusters

Superfamily	5' to 3' exonuclease, C-terminal subdomain
Functional Family	exonuclease 1

Enzyme Information

3.1.-.-

Acting on ester bonds.

based on mapping to UniProt Q9UQ84

UniProtKB Entries (1)

EXO1_HUMAN

Homo sapiens

Exonuclease 1

PDB Structure

PDB	3QEB
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structures of human exonuclease 1 DNA complexes suggest a unified mechanism for nuclease family. Orans, J., McSweeney, E.A., Iyer, R.R., Hast, M.A., Hellinga, H.W., Modrich, P., Beese, L.S. Cell(Cambridge,Mass.)