CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family | Shikimate dehydrogenase (NADP(+)) |
Enzyme Information
| 1.1.1.25 |
Shikimate dehydrogenase.
based on mapping to UniProt Q9KVT3
Shikimate + NADP(+) = 3-dehydroshikimate + NADPH.
-!- NAD(+) cannot replace NADP(+). -!- In higher organisms, this enzyme forms part of a multienzyme complex with EC 4.2.1.10.
|
UniProtKB Entries (1)
| Q9KVT3 |
AROE_VIBCH
Vibrio cholerae O1 biovar El Tor str. N16961
Shikimate dehydrogenase (NADP(+))
|
PDB Structure
| PDB | 3PGJ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
2.49 Angstrom resolution crystal structure of shikimate 5-dehydrogenase (aroE) from Vibrio cholerae O1 biovar eltor str. N16961 in complex with shikimate
To be Published
|