CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.510 | Transferase(Phosphotransferase); domain 1 | |
1.10.510.10 | Transferase(Phosphotransferase) domain 1 |
Domain Context
CATH Clusters
Superfamily | Transferase(Phosphotransferase) domain 1 |
Functional Family | 3-phosphoinositide-dependent protein kinase 1 |
Enzyme Information
2.7.11.1 |
Non-specific serine/threonine protein kinase.
based on mapping to UniProt O15530
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.
|
UniProtKB Entries (1)
O15530 |
PDPK1_HUMAN
Homo sapiens
3-phosphoinositide-dependent protein kinase 1
|
PDB Structure
PDB | 3ORZ |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Turning a protein kinase on or off from a single allosteric site via disulfide trapping.
Proc.Natl.Acad.Sci.USA
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