CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase(Phosphotransferase) domain 1
Functional Family 3-phosphoinositide-dependent protein kinase 1

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt O15530
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

O15530
PDPK1_HUMAN
Homo sapiens
3-phosphoinositide-dependent protein kinase 1

PDB Structure

PDB 3ORZ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Turning a protein kinase on or off from a single allosteric site via disulfide trapping.
Sadowsky, J.D., Burlingame, M.A., Wolan, D.W., McClendon, C.L., Jacobson, M.P., Wells, J.A.
Proc.Natl.Acad.Sci.USA