CATH Domain 3o10D00

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.120	Four Helix Bundle (Hemerythrin (Met), subunit A)
	1.20.120.330	Nucleotidyltransferases domain 2

Domain Context

CATH Clusters

Superfamily	Nucleotidyltransferases domain 2
Functional Family	Sacsin molecular chaperone

Enzyme Information

UniProtKB Entries (1)

SACS_HUMAN

Homo sapiens

Sacsin

PDB Structure

PDB	3O10
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural basis of defects in the sacsin HEPN domain responsible for autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS). Kozlov, G., Denisov, A.Y., Girard, M., Dicaire, M.J., Hamlin, J., McPherson, P.S., Brais, B., Gehring, K. J.Biol.Chem.