CATH Domain 3nc2A00

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.1190	UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase
	3.40.1190.20	Ribokinase

Superfamily	3.40.1190.20
Functional Family	Ketohexokinase

2.7.1.3

Ketohexokinase.

based on mapping to UniProt P50053

ATP + D-fructose = ADP + D-fructose 1-phosphate.

-!- D-sorbose, D-agatose and 5-dehydro-D-fructose also act as acceptors.

KHK_HUMAN

Homo sapiens

Ketohexokinase

PDB	3NC2
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Electron density guided fragment-based lead discovery of ketohexokinase inhibitors. Gibbs, A.C., Abad, M.C., Zhang, X., Tounge, B.A., Lewandowski, F.A., Struble, G.T., Sun, W., Sui, Z., Kuo, L.C. J.Med.Chem.